Advanced Optical Imaging for Biomedicine

Optical imaging provides a direct way to inspect biological and medical objects. Rapid developments of novel optical imaging technology and instruments can lead to significant breakthroughs in understanding fundamental biological phenomena and rapid diagnosis of diseases such as Optical Coherence Tomography, Photo-acoustic Imaging, Stimulated Resonance Raman Imaging, Multiphoton Microscopy, Super-Resolution Microscopy, and many others. Some technologies have been translated to biomedical applications, and some are on the doorstep. Joint efforts from both optical and biomedical communities are still needed to fully discover the potential of these optical modalities and promote them as routine laboratory and/or clinical apparatus.

This special issue calls for papers reporting on the latest progress of optical imaging for biomedicine in theory, instrumentation, and application. Original research papers and review articles are both welcome. Topics include but are not limited to:

• Photoacoustic imaging
• Resonance Raman imaging (CARS or SRS)
• Optical coherent tomography (OCT) for clinic applications
• Optical endoscopy
• Optical imaging guided surgery
• Optical microscopy for biology and pathology
• Machine learning and deep learning in optical imaging

Please indicate in your cover letter that your submission is intended for inclusion in the special issue, Advanced Optical Imaging for Biomedicine.

As articles within the special issue are published they will appear below.

Emerging Advances to Transform Histopathology Using Virtual Staining

Yair Rivenson, Kevin de Haan, W. Dean Wallace, and Aydogan Ozcan

BME Frontiers, vol. 2020, Article ID 9647163, 11 pages, 2020

Terahertz Imaging and Spectroscopy in Cancer Diagnostics: A Technical Review

Yiming Zhu, Yan Peng, Chenjun Shi, Xu Wu, and Songlin Zhuang

BME Frontiers, vol. 2020, Article ID 2547609, 11 pages, 2020

From Neurons to Cognition: Technologies for Precise Recording of Neural Activity Underlying Behavior

Richard H. Roth, Jun B. Ding

BME Frontiers, vol. 2020, Article ID 7190517, 20 pages, 2020

Anatomical Modeling of Brain Vasculature in Two-Photon Microscopy by Generalizable Deep Learning

Waleed Tahir, Sreekanth Kura, Jiabei Zhu, Xiaojun Cheng, Rafat Damseh, Fetsum Tadesse, Alex Seibel, Blaire S. Lee, Frédéric Lesage, Sava Sakadžic, David A. Boas, Lei Tian

BME Frontiers, vol. 2021, Article ID 8620932, 12 pages, 2021

Recent Advancements in Optical Harmonic Generation Microscopy: Applications and Perspectives

Darian S. James, Paul J. Campagnola

BME Frontiers, vol. 2021, Article ID 3973857, 24 pages, 2021

Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease

Alicia Megia-Fernandez, Adam Marshall, Ahsan R. Akram, Bethany Mills, Sunay V. Chankeshwara, Emma Scholefield, Amy Miele, Bruce C. McGorum, Chesney Michaels, Nathan Knighton, Tom Vercauteren, Francois Lacombe, Veronique Dentan, Annya M. Bruce, Joanne Mair, Robert Hitchcock, Nik Hirani, Chris Haslett, Mark Bradley, Kevin Dhaliwal

BME Frontiers, vol. 2021, Article ID 9834163, 11 pages, 2021