Advanced Optical Imaging for Biomedicine

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Optical imaging provides a direct way to inspect biological and medical objects. Rapid developments of novel optical imaging technology and instruments can lead to significant breakthroughs in understanding fundamental biological phenomena and rapid diagnosis of diseases such as Optical Coherence Tomography, Photo-acoustic Imaging, Stimulated Resonance Raman Imaging, Multiphoton Microscopy, Super-Resolution Microscopy, and many others. Some technologies have been translated to biomedical applications, and some are on the doorstep. Joint efforts from both optical and biomedical communities are still needed to fully discover the potential of these optical modalities and promote them as routine laboratory and/or clinical apparatus.

This special issue calls for papers reporting on the latest progress of optical imaging for biomedicine in theory, instrumentation, and application. Original research papers and review articles are both welcome. Topics include but are not limited to:

  • Photoacoustic imaging
  • Resonance Raman imaging (CARS or SRS)
  • Optical coherent tomography (OCT) for clinic applications
  • Optical endoscopy
  • Optical imaging guided surgery
  • Optical microscopy for biology and pathology
  • Machine learning and deep learning in optical imaging

    Table of Contents

    As articles within the special issue are published they will appear below.

    Emerging Advances to Transform Histopathology Using Virtual Staining

    Yair Rivenson, Kevin de Haan, W. Dean Wallace, and Aydogan Ozcan

    BME Frontiers, vol. 2020, Article ID 9647163, 11 pages, 2020

    Terahertz Imaging and Spectroscopy in Cancer Diagnostics: A Technical Review

    Yiming Zhu, Yan Peng, Chenjun Shi, Xu Wu, and Songlin Zhuang

    BME Frontiers, vol. 2020, Article ID 2547609, 11 pages, 2020

    From Neurons to Cognition: Technologies for Precise Recording of Neural Activity Underlying Behavior

    Richard H. Roth, Jun B. Ding

    BME Frontiers, vol. 2020, Article ID 7190517, 20 pages, 2020

    Anatomical Modeling of Brain Vasculature in Two-Photon Microscopy by Generalizable Deep Learning

    Waleed Tahir, Sreekanth Kura, Jiabei Zhu, Xiaojun Cheng, Rafat Damseh, Fetsum Tadesse, Alex Seibel, Blaire S. Lee, Frédéric Lesage, Sava Sakadžic, David A. Boas, Lei Tian

    BME Frontiers, vol. 2021, Article ID 8620932, 12 pages, 2021

    Recent Advancements in Optical Harmonic Generation Microscopy: Applications and Perspectives

    Darian S. James, Paul J. Campagnola

    BME Frontiers, vol. 2021, Article ID 3973857, 24 pages, 2021

    Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease

    Alicia Megia-Fernandez, Adam Marshall, Ahsan R. Akram, Bethany Mills, Sunay V. Chankeshwara, Emma Scholefield, Amy Miele, Bruce C. McGorum, Chesney Michaels, Nathan Knighton, Tom Vercauteren, Francois Lacombe, Veronique Dentan, Annya M. Bruce, Joanne Mair, Robert Hitchcock, Nik Hirani, Chris Haslett, Mark Bradley, Kevin Dhaliwal

    BME Frontiers, vol. 2021, Article ID 9834163, 11 pages, 2021

    Recent Advances in Photoacoustic Tomography

    Lei Li, Lihong V. Wang

    BME Frontiers, vol. 2021, Article ID 9823268, 17 pages, 2021