BioDesign Research / 2021 / Article / Fig 5

Research Article

In-Depth Computational Analysis of Natural and Artificial Carbon Fixation Pathways

Figure 5

Design of a pathway to convert acetyl-CoA (Ac-CoA) to pyruvate (Pyr) using parts of the reductive citramalyl-CoA cycle (blue) and the ethylmalonyl-CoA pathway (grey). The dashed arrow denotes the possible recycling of acetyl-CoA for the first reaction of the ethylmalonyl-CoA pathway. Abbreviations: EM-CoA: ethylmalonyl-CoA; Mesac-CoA: mesaconyl-CoA; CitMal-CoA: citramalyl-CoA; Ac-CoA: acetyl-CoA; Pyr: pyruvate; AcAc-CoA: acetoacetyl-CoA; 3-HB-CoA: 3-hydroxybutyryl-CoA.