Cyborg and Bionic Systems / 2021 / Article / Fig 1

Research Article

Cell-Based Biohybrid Sensor Device for Chemical Source Direction Estimation

Figure 1

Schematic of the proposed cell-based biohybrid sensor. Collagen hydrogel embedded with sensor cells is placed in each chamber of the microfabricated octagonal separator device. The fluorescence emission of the calcium indicator in the cells reacting to the chemical of interest is detected through a microscopic lens. The direction of the chemical source can be calculated by observing the time course of the fluorescence change in each chamber.