Cell-Based Biohybrid Sensor Device for Chemical Source Direction Estimation
(a) Changes in fluorescence intensity at each region of interest (ROI) of the cell-based biohybrid sensor. The ROI numbers were assigned as shown in the image. The black arrow indicates the timing of peak detection. (b) Time of peak intensity () at each ROI. (c) Curve fitted by means of a sinusoidal approximation to the time of peak intensity. Each ROI number was converted into the corresponding angle, and subsequently, the angle that minimized according to the curve was estimated as the direction of the chemical source. Scale bar: 500 μm.