Research / 2018 / Article / Fig 1

Review Article

Passing the Baton: Substrate Channelling in Respiratory Metabolism

Figure 1

The metabolon of the TCA cycle. (a) The plant protein interactions of catalytic subunits that potentially mediate metabolite channelling are described next to the arrows. Metabolites drawn as red, grey, and black text are channelled, not channelled, and not tested, respectively [53]. (b) The protein structure of the metabolon MDH-CSY-ACO with the active sites (red spheres) [54, 55]. PDC, pyruvate dehydrogenase complex; ME, malic enzyme; CSY, citrate synthase; ACO, aconitase; IDH, isocitrate; ODC, oxoglutarate dehydrogenase complex; SCoAL, succinyl-CoA ligase; SDH, succinate dehydrogenase; FUM, fumarase; MDH, malate dehydrogenase; 2OG, 2-oxoglutarate.