(◊) Immunity means the type of immunity induced by the adjuvant, as reported in the literature and not the one described for the vaccine in question. () CRM197 nontoxic diphtheria toxin. () Alum a traditionally assumed Th2 adjuvant has many proinflammatory properties [67, 68]. (§) VLP are virus-like-particles derived from Qβ phage. () UBITh is a proprietary set of T helper epitopes derived from MVT, PT and TT . (▲) MPLA monophosphoryl lipid A.