Centimeter-Deep NIR-II Fluorescence Imaging with Nontoxic AIE Probes in Nonhuman Primates
Histological images of the major organs of one randomly selected cynomolgus monkey at the end of 36 days after IV injection of AIE probes. Evaluations were performed by two pathologists, and no anomalies were observed. Tissues were collected from the heart, liver, spleen, lung, kidney, brain, pancreas, small intestine, large intestine, stomach, muscle, and lymph node. Images were taken at ×40 magnification with standard hematoxylin and eosin staining.
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