Research / 2020 / Article / Fig 8

Review Article

Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community

Figure 8

Proposed schematic of 2019-nCoV replication and potential treatment options targeting the coronavirus replication cycle. ACE2: angiotensin-converting enzyme 2; +: positive-strand RNA; AP: accessory protein; E: envelope protein; ER: endoplasmic reticulum; N: nucleocapsid protein; M: membrane protein; ERGIC: endoplasmic reticulum-Golgi intermediate compartment; S: spike glycoprotein.