Research / 2020 / Article / Fig 1

Review Article

Smart Microneedles for Therapy and Diagnosis

Figure 1

Schematic illustrations of fabrication strategies. (a) A typical four-step fabrication method. (b) Fabrication of two-layer microneedles. (c) Fabrication of three-layer microneedles. (d) Fabrication of coating microneedles. (e) Two-step heating transfer molding: (i) mold filling and tip solidification; (ii) tip-substrate connection. Reproduced with permission from Ref. [24], copyright 2013, Wiley-VCH. (f) Transfer molding to fabricate microneedles on a surgical mesh. Reproduced with permission from Ref. [25], copyright 2017, Elsevier B.V. (g) Spin coating process. Reproduced with permission from Ref. [26], copyright 2017, Elsevier B.V. (h) Electrodrawing method. Reproduced with permission from Ref. [17], copyright 2014, Wiley-VCH. (i) Droplet-born air blowing method. Reproduced with permission from Ref. [18], copyright 2013, Elsevier B.V.