Research / 2020 / Article / Tab 2

Review Article

Smart Microneedles for Therapy and Diagnosis

Table 2

Tip materials for dissolvable microneedles.

MaterialPolymerizationDissolving timeRef.

Polyvinylpyrrolidone (PVP)Photopolymerization or drying~5 min[2]
Hyaluronic acid (HA)Drying or centrifugal evaporation2-30 min[37]
Polyvinyl alcohol (PVA)Drying2-30 min[38]
Poly(ethylene glycol) (PEG)DryingLess than 30 min[39]
Dextran and sorbitolDrying~5 min[40]
GelatinDrying~15 min[41]
Hydroxyethyl starch (HES)Drying~10 min[42]
Carboxymethyl cellulose (CMC)Drying2-30 min[43]
TrehaloseDrying, dehydration3-20 min[44]
Poly-γ-glutamic acid (γ-PGA)DryingLess than 4 min[45]

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