Synergistically Enhanced Mucoadhesive and Penetrable Polypeptide Nanogel for Efficient Drug Delivery to Orthotopic Bladder Cancer
In vivo anti-tumor efficacy on orthotopic BC in C57Bl/6 mice. (a) Cystography and (b) external and internal surface of bladders after intravesical chemotherapy with PBS as a control, free HCPT, NG/HCPT, or R9NG/HCPT. (c) Evolution of body weight and (d) survival rate during the experiments. The scale bars represent (a) 1.0 cm and (b) 0.5 cm, respectively. Data are presented as ().