Spheroids of Endothelial Cells and Vascular Smooth Muscle Cells Promote Cell Migration in Hyaluronic Acid and Fibrinogen Composite Hydrogels
Migration distance of EC, SMC, and EC-SMC spheroids in different hydrogels after being cultured for (a) 4, (b) 7, and (c) 14 days. The migration distance is defined as the entire diameter of the cell contour minuses the diameter of the cell spheroid. (d) For the convenient and direct comparison, the migration distance of EC-SMC spheroids cultured in different hydrogels was replotted vs. culture time. indicates significant difference at level.