Transcriptomic analysis. In the figure, A and B represent the control and the GOD/CAT@ZPF-Lips group, respectively. (a) Statistics of the differentiated genes between group A and group B. (b) Genome circle map and (c) the volcano plot showing the distribution of genes and the results of significant differences in genes after treated by GOD/CAT@ZPF-Lips. (d) The heat map representation of differentially expressed genes which altered mRNA transcripts in 4T1 cells. (e) GO and (f) KEGG enrichment analysis for studying the underlying pathways of GOD/CAT@ZPF-Lips treatment.