Starvation-Sensitized and Oxygenation-Promoted Tumor Sonodynamic Therapy by a Cascade Enzymatic Approach
In vivo biological behavior of GOD/CAT@ZPF-Lips. (a) Blood-circulation lifetime of GOD/CAT@ZPF-Lips in mice after intravenous administration via tail veins (). (b) Biodistribution of Zn2+ after injecting GOD/CAT@ZPF-Lips (20 mg kg-1) into the mice for 4, 8, 12, and 24 h. (c) Body weights of Kunming mice treated under different conditions during 30 days of feeding. (e, d) Hematological assays of Kunming mice in 30 days posttreatment in different conditions.