Research / 2021 / Article / Fig 5

Review Article

Low-Temperature Photothermal Therapy: Strategies and Applications

Figure 5

(a) Scheme of the enhanced cancer therapeutic efficiency of mild PTT resulting from photothermal sensitization through CQ-mediated autophagy inhibition. Reprinted with permission from Reference [129]. Copyright 2017, Elsevier Ltd. (b) Multistep preparation process of the rattle-structured PDA@hm@CQ@GOx NP. (c) Schematic illustration of the working mechanism of PDA@hm@CQ@GOx NPs that can achieve enhanced low-temperature PTT under NIR light irradiation. (b, c) Reprinted with permission from Reference [131]. Copyright 2020, Ivyspring. (d) Scheme depicting the beclin 1-induced autophagy rendering cancer cells vulnerable to photothermal elimination. Reprinted with permission from Reference [133]. Copyright 2019, Elsevier Ltd. (e) Scheme illustrating the Hf-HI-4COOH NCP structure and nucleus-targeted low-temperature PTT. Reprinted with permission from Reference [142]. Copyright 2020, Elsevier Ltd. (f) Scheme depicting the synthesis of PEG-PtCNPs and PEG-PtCNPs-RITC and their application for multimodal imaging-guided and multiorganelle-targeted PTT. Reprinted with permission from Reference [145]. Copyright 2018, Elsevier Ltd.