Research / 2022 / Article / Fig 1

Research Article

trans-2-Enoyl-CoA Reductase Tecr-Driven Lipid Metabolism in Endothelial Cells Protects against Transcytosis to Maintain Blood-Brain Barrier Homeostasis

Figure 1

Transcriptomic characterization of P5-P21 LGN and Tecr expression. (a) t-SNE plot of cells extracted from P5, P10, P16, and P21 LGN. (b) Expression pattern of cluster markers defined different cell types. (c) t-SNE plot of cell types (inhibitory neuron, excitatory neuron, oligodendrocyte, endothelial, pericyte, astrocyte, macrophage, and microglia). (d) t-SNE plot of ECs subclusters. (e) t-SNE plot of ECs extracted from P5, P10, P16, and P21 LGN. (f) Proportions of Tecr- (blue) and Tecr+ (red) cells for P5, P10, P16, and P21 LGN. (g) Violin plots of the expression of Tecr at P5, P10, P16, and P21 stages’ ECs. (h) Violin plots of the expression of Tecr in the indicated tissues’ ECs.