Research / 2022 / Article / Fig 6

Research Article

Platelet Membrane-Coated Nanocarriers Targeting Plaques to Deliver Anti-CD47 Antibody for Atherosclerotic Therapy

Figure 6

(a) Illustration of aCD47@PMSN promoted phagocytosis of necrotic smooth muscle cells. (b) IHC analysis of aortic roots from ApoE−/− mice after various treatments (CD68, α-SMA, and CD31). (c) Quantitative data of the macrophages in the aortic root sections (PBS: , aCD47: , aCD47@MSN: , aCD47@PMSN: ). (d) Quantitative data of the smooth muscle cells in the aortic root sections (PBS: , aCD47: , aCD47@MSN: , aCD47@PMSN: ). (e) Quantitative data of the endothelial cells in the aortic root sections (PBS: , aCD47: , aCD47@MSN: , aCD47@PMSN: ). , , , , and . ns: no significance.