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Research Article

Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery

Hong-Yan Lin1,2, Xi Chen3, Jia-Nan Chen1, Da-Wei Wang1, Feng-Xu Wu1, Song-Yun Lin2, Chang-Guo Zhan4, Jia-Wei Wu2, Wen-Chao Yang1, and Guang-Fu Yang1,5

1Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Chemical Biology Center, Central China Normal University, Wuhan 430079, China
2MOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China
3College of Chemistry and Material Science, South-Central University for Nationalities, Wuhan 430074, China
4Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, USA
5Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 30071, China
Correspondence should be addressed to Wen-Chao Yang; tomyang@mail.ccnu.edu.cn and Guang-Fu Yang; gfyang@mail.ccnu.edu.cn

How to Cite this Article

Hong-Yan Lin, Xi Chen, Jia-Nan Chen, et al., “Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery,” Research, vol. 2019, Article ID 2602414, 11 pages, 2019. https://doi.org/10.34133/2019/2602414.

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